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Lung Transplant and Injury Research Lab

The Lung Transplant and Injury Research Lab in the Department of Surgery is comprised of a diverse team of clinicians, faculty, staff, and students dedicated to helping patients through the advancement of basic and translational research as well as providing research training to Residents, PostDocs, and Students. Our lab utilizes both in vivo and in vitro models to study clinically relevant issues including: mechanisms of lung ischemia-reperfusion injury after transplant, organ preservation, ex vivo lung perfusion (EVLP), in vivo lung perfusion (IVLP), dermal burn wounds, and organ injury after cardiopulmonary bypass.

Resident researh team

Team

Our Resident Research team (L-R): Matthew Weber, MD, Steven Young, MD, Anthony Norman, MD, Alex Wisniewski, MD, and Sean Noona, MD.

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Lung SPECT imaging

Research

Our lab has multiple research projects underway including: 1) role of TRPV4 and Piezo1 channels in lung ischemia-reperfusion injury (IRI) after transplant, 2) testing therapeutic strategies to prevent IRI, 3) vascular endothelial barrier, 4) reconditioning lungs via EVLP, and 5) IVLP-mediated attenuation of ARDS.

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Surgical training

Training

A huge component of our lab is the research training provided to residents, postdocs and students. Our surgery residents receive formal, mentor-guided research training through our NIH/NHLBI T32-funded CardioVascular Surgery Training Program (CVSTP).

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Be An Organ Donor

You can save many lives by being an organ donor.

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